At the turn of the 20th century, people in Missouri experienced unexpected and horrible deaths due to arsenic. Two different women in two different areas of Missouri, and for two different reasons, used arsenic as a means to get what they wanted. Emma Heppermann, a black widow killer, craved money. Bertha Gifford, an angel of mercy, took sick people into her home and nursed them to death. Follow the trails of these women who murdered for decades before being tried and convicted. From Wentzville to Steelville, Emma left a trail of bodies. And Bertha is suspected of killing almost 10% of the population of the little town of Catawissa. Author Victoria Cosner offers the gruesome history of these murderous matrons.